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Chitosan For Weight Loss?

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I’ve been doing some research on chitosan. It sounds like a dream come true for weight-watchers, but I’m concerned because I haven’t been able to find information on it. It seems that chitosan might deplete your system of fat-soluble vitamins.

Stansbury responds: Chitosan (pronounced “kite-o-san”) is derived from chitin, a fiber-like compound obtained from the tough exoskeletons of marine shellfish. The chitin is processed to create a biopolymer (a naturally occurring chain-like molecule) that forms a gel-like substance in the intestines.

Like many natural fibers, gums, and pec-tins, chitosan is reported to trap ingested fats within the intestines, preventing their ab-sorption. Also, like many fibers and related compounds, chitosan is reported to reduce the synthesis of new cholesterol and improve the HDL to LDL ratio.

Furthermore, chitosan does interfere with the absorption of fat-soluble vitamins. While it doesn’t “deplete” your body of fat-soluble vitamins, it can usurp the vitamins and nutrients present in the fat that it traps. Though unlikely to promote frank nutritional deficiencies, chitosan can easily trap nutrients, just as the fiber can trap fat.

Also, I confess to having some concerns with grinding up shellfish exoskeletons to manage our weight or cholesterol. The fiber in legumes, the pectin in apples, or the gums in oatmeal and seaweed, for example, have also been shown to trap lipids and benefit cholesterol levels. To me, these foods seem to be a kinder, gentler choice in medicine.

Willard responds: You’re right—chitosan is both a dream come true and an area of concern for consumers. This fiber substance is another form of roughage that we know can be good for us. Like some plant fibers, it’s not digestible and therefore has no caloric value. Research on chitosan as a natural weight loss agent, as a fiber for adding bulk to the digestive system, and for colon cleansing dates back more than seventeen years.

Chitosan has been shown to absorb and bind fats (promoting weight loss), inhibit LDL cholesterol, boost HDL cholesterol, and promote healing of ulcers and lesions, among other actions.

Within the digestive system, chitosan dissolves and forms a positively charged gel. Negatively charged molecules of fats, lipids, and bile attach strongly to the chitosan, causing large polymer compounds to be formed that can’t be broken down by the digestive process. Herein lies the double-edged sword. Not only can chitosan bind the food you do not want to absorb, but it can also inhibit nutrients. The bioavailability of fat-soluble vitamins or medications will be inhibited if taken with chitosan. Also, people with shellfish allergies and women who are pregnant or breastfeeding should not take the supplement. As with any kind of fiber supplement, one should also drink six to eight glasses of water a day to prevent constipation.

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