Shiitake
Medicine in a mushroom
January/February 1997
By Kenneth Jones
Mushrooms are a fascinating class of life form:
vast underground mycelia that push up strange fruiting bodies when
climatic conditions are right, and a vast range of forms—from
common fairy rings and puffballs to strange, unearthly, pale violet
discs; from tiny pinheads to hubcap-sized saucers. Of an estimated
100,000 species of mushrooms, most are edible and very nutritious,
containing large amounts of protein, fiber, minerals (including
calcium), B vitamins, and vitamin C.
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Shiitake (shee-TAH-kee) mushrooms are a culinary rage in the
United States today (you can even buy kits for growing your own),
but have been important in Chinese culture for thousands of years.
One of the earliest recorded uses of shiitake (Lentinula edodes)
dates as far back as the fourteenth century, when the Chinese
physician Wu-Rui described it as a food that accelerates vital or
“spirit” energy (known as Qi in Chinese), staves off hunger, “cures
cold, and penetrates into the blood circulatory system.” Today,
these attributes are collectively taken to mean that shiitake makes
a person more lively. Wu also stated that shiitake was “good for
treatment of Heart Troubles . . . beneficial to [all forms of]
Malignancy, likewise certainly [good for] Snake’s poison.” For the
past thirty years, scientists have been investigating some of these
uses and have amassed evidence that shiitake can help the body
fight heart disease, cancer, and viral diseases. Most of the
research has been carried out in Japan. Some of the studies are
discussed below.
Heart disease
The body could not function without cholesterol, which helps the
body break down fats, or lipids, in the small intestine so that
they can be absorbed into the bloodstream. In the liver,
cholesterol combines with lipids and proteins in the blood to form
various complexes called lipoproteins. A large proportion of
low-density lipoproteins (LDL or “bad” cholesterol) in the blood
has been linked to clogged artery walls, which can lead to heart
attack or stroke. High-density lipoproteins (HDL or “good”
cholesterol), on the other hand, have been shown to scavenge excess
LDL from the bloodstream and carry it to the liver for excretion or
processing into good cholesterol.
According to studies performed in Japan during the 1970s,
shiitake contains an amino acid called eritadenine that accelerates
cholesterol’s processing in the liver. In addition, shiitake’s high
dietary fiber helps the body process cholesterol.
In a 1974 study, 40 elderly people and 420 young women ate 9 g
of dried shiitake or the equivalent amount of fresh shiitake (90 g)
daily. After seven days, total cholesterol level (the types of
cholesterol affected were not distinguished) had decreased 7 to 15
percent in the elderly and 6 to 12 percent in the young women.
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